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Lester I Binder Selected Research

Pick Disease of the Brain (Pick's Disease)

1/2012Selective tau tyrosine nitration in non-AD tauopathies.
9/2011X-ray diffraction from intact tau aggregates in human brain tissue.
5/2007Phosphorylation and cleavage of tau in non-AD tauopathies.
1/2007Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies.
10/2003The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy.

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Lester I Binder Research Topics

Disease

32Alzheimer Disease (Alzheimer's Disease)
01/2016 - 04/2002
16Tauopathies
07/2014 - 09/2006
7Neurodegenerative Diseases (Neurodegenerative Disease)
08/2012 - 12/2003
5Pick Disease of the Brain (Pick's Disease)
01/2012 - 10/2003
3Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
01/2012 - 01/2007
3Corticobasal Degeneration
01/2012 - 01/2007
3Frontotemporal Dementia (Semantic Dementia)
04/2008 - 02/2003
3Amyloid Plaque
07/2005 - 04/2002
2Neuroblastoma
01/2013 - 06/2008
2Cognitive Dysfunction
11/2011 - 11/2011
2Disease Progression
11/2011 - 12/2009
2Dementia (Dementias)
04/2006 - 09/2004
1Premature Aging
01/2013
1Inflammation (Inflammations)
02/2011
1Infections
06/2008
1Parkinson Disease (Parkinson's Disease)
06/2007
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
06/2007

Drug/Important Bio-Agent (IBA)

17tau Proteins (tau Protein)IBA
01/2016 - 04/2002
14Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
04/2012 - 12/2003
6Tyrosine (L-Tyrosine)FDA Link
01/2012 - 10/2006
5Proteins (Proteins, Gene)FDA Link
08/2008 - 04/2002
3Amyloid (Amyloid Fibrils)IBA
08/2012 - 08/2003
2AntibodiesIBA
07/2014 - 01/2012
2Caspase 3 (Caspase-3)IBA
12/2013 - 06/2008
2Peptides (Polypeptides)IBA
08/2012 - 04/2002
2Aspartic Acid (Aspartate)FDA Link
03/2012 - 05/2006
2Protein Isoforms (Isoforms)IBA
01/2012 - 10/2003
2EpitopesIBA
11/2011 - 07/2005
2Peroxynitrous Acid (Peroxynitrite)IBA
02/2011 - 02/2005
2CaspasesIBA
06/2008 - 08/2003
2Glycogen Synthase Kinase 3 betaIBA
06/2008 - 04/2008
1LaminsIBA
01/2013
1PolymersIBA
01/2013
1UbiquitinIBA
03/2012
1Cholinergic Agents (Cholinergics)IBA
11/2011
1Proline (L-Proline)FDA Link
05/2011
1NitrogenIBA
02/2011
1Oxygen (Dioxygen)IBA
02/2011
1JNK Mitogen-Activated Protein KinasesIBA
06/2008
1EnzymesIBA
04/2008
1Glycogen Synthase (Synthase I)IBA
04/2008
1alpha-SynucleinIBA
06/2007
1Superoxide DismutaseIBA
06/2007
1Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA
06/2007
1enkephalin degrading enzymeIBA
09/2006
1Serine (L-Serine)FDA Link
05/2006
1dityrosineIBA
02/2005
1Caspase 6IBA
09/2004
1Carrier Proteins (Binding Protein)IBA
08/2003
1Leucine (L-Leucine)FDA Link
02/2003
1Arginine (L-Arginine)FDA Link
02/2003
1Amyloid beta-PeptidesIBA
04/2002

Therapy/Procedure

1Therapeutics
10/2012